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  • ARTICLE – Safety Analysis Insight: Medication errors reported with methotrexate

ARTICLE – Safety Analysis Insight: Medication errors reported with methotrexate

written by Ivona Bahnik Bisevac, PV Director of Benefit-Risk Management, Bojana Milasinovic, Senior PV Physician, and Katarina Stamatovic, Medical Reviewer

A medication error is an unintended failure in the drug treatment process that leads to, or has the potential to lead to, harm to the patient. Mistakes in the prescribing, dispensing, storing, preparation and administration of a medicine are the most common preventable cause of undesired adverse events in medication practice and present a major public health burden (European Medicines Agency, 2022). The risks associated with inappropriate use of methotrexate daily instead of weekly make methotrexate one of the most known high-risk medications prone to medication errors. Systematic review revealed that 47% of all serious medication errors were caused by only seven drug classes, with methotrexate topping the list in percentage of incidents (Saedder EA, 2014).

Authors
  • Ivona Bahnik Bisevac, PV Director of Benefit-Risk Management
  • Bojana Milasinovic, Senior PV Physician
  • Katarina Stamatovic, Medical Reviewer

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